| Date | Location | Result | |
| 03/01/22 | Caldwell, Idaho (J.A. Albertson Ctr.) | College of Idaho 78, Southern Oregon 55 | Box score |
| 02/26/22 | Lewiston, Idaho (P1FCU Activity Center) | Southern Oregon 67, Lewis-Clark State 66 | Box score |
| 02/23/22 | Salem, Ore. (C.E. Jeffers Sports Center) | Southern Oregon 67, Corban 65 | Box score |
| 02/19/22 | College Place, Wash. (Windemuth Court) | Walla Walla 72, Southern Oregon 71 | Box score |
| 02/18/22 | Lewiston, Idaho (P1FCU Activity Center) | Lewis-Clark State 72, Southern Oregon 66 | Box score |
| 02/12/22 | Ashland, Ore. (Lithia Motors Pavilion) | Southern Oregon 66, Multnomah 42 | Box score |
| 02/11/22 | Ashland, Ore. (Lithia Motors Pavilion) | Southern Oregon 60, Warner Pacific 54 | Box score |
| 02/08/22 | Klamath Falls, Ore. Danny Miles Court | Oregon Tech 79, Southern Oregon 73 | Box score |
| 02/05/22 | Eugene, Ore. (Morse Events Center) | Southern Oregon 70, Bushnell 68 | Box score |
| 02/04/22 | Salem, Ore. (C.E. Jeffers Sports Center) | Corban 87, Southern Oregon 80 (OT) | Box score |
| 01/29/22 | Ashland, Ore. (Lithia Motors Pavilion) | Southern Oregon 96, Evergreen 84 | Box score |
| 01/28/22 | Ashland, Ore. (Lithia Motors Pavilion) | Southern Oregon 63, Northwest 59 | Box score |
| 01/22/22 | La Grande, Ore. (Quinn Coliseum) | Eastern Oregon 65, Southern Oregon 62 | Box score |
| 01/21/22 | Caldwell, Idaho (J.A. Albertson Ctr.) | College of Idaho 97, Southern Oregon 47 | Box score |
| 01/14/22 | Portland, Ore. (Lytle Gymnasium) | Southern Oregon 99, Multnomah 75 | Box score |
| 01/07/22 | Ashland, Ore. (Lithia Motors Pavilion) | Southern Oregon 84, Walla Walla 78 | Box score |
| 01/02/22 | Kirkland, Wash. (Kirsti Brodin Pavilion) | Southern Oregon 72, Northwest 69 | Box score |
| 01/01/22 | Olympia, Wash. (Costantino Rec Center) | Southern Oregon 103, Evergreen 65 | Box score |
| 12/18/21 | Ashland, Ore. (Lithia Motors Pavilion) | Southern Oregon 75, Corban 69 | Box score |
| 12/17/21 | Ashland, Ore. (Lithia Motors Pavilion) | Bushnell 76, Southern Oregon 71 | Box score |
| 12/04/21 | Ashland, Ore. (Lithia Motors Pavilion) | College of Idaho 66, Southern Oregon 49 | Box score |
| 12/03/21 | Ashland, Ore. (Lithia Motors Pavilion) | Southern Oregon 70, Eastern Oregon 67 | Box score |
| 11/30/21 | Redding, Calif. (Grant Center) | Simpson 73, Southern Oregon 55 | Box score |
| 11/26/21 | Ashland, Ore. (Lithia Motors Pavilion) | Southern Oregon 77, Antelope Valley 57 | Box score |
| 11/23/21 | Ashland, Ore. (Lithia Motors Pavilion) | Oregon Tech 77, Southern Oregon 61 | Box score |
| 11/20/21 | Ashland, Ore. (Lithia Motors Pavilion) | Southern Oregon 55, Park Gilbert 50 | Box score |
| 11/19/21 | Ashland, Ore. (Lithia Motors Pavilion) | Montana Tech 73, Southern Oregon 68 | Box score |
| 11/13/21 | Klamath Falls, Ore. (Danny Miles Court) | Southern Oregon 105, Embry Riddle 74 | Box score |
| 11/12/21 | Klamath Falls, Ore. (Danny Miles Court) | William Jessup 77, Southern Oregon 75 | Box score |
| 11/06/21 | Santa Clarita, Calif. (MacArthur Center) | The Master's 82, Southern Oregon 76 | Box score |
| 11/05/21 | Santa Barbara, Calif. (Murchison Gym) | Westmont 67, Southern Oregon 66 | Box score |