| Date | Location | Result | |
| 11/06/21 | Ashland, Ore. | Southern Oregon 3, Warner Pacific 0 (25-12,25-18,25-11) | Box score |
| 11/05/21 | Ashland, Ore. | Southern Oregon 3, Multnomah 0 (25-14,25-23,25-20) | Box score |
| 10/30/21 | Caldwell, Idaho | College of Idaho 3, Southern Oregon 0 (25-21,25-19,26-24) | Box score |
| 10/29/21 | La Grande, Ore. | Eastern Oregon 3, Southern Oregon 0 (25-17,25-14,25-19) | Box score |
| 10/23/21 | Ashland, Ore. | Corban 3, Southern Oregon 0 (25-13,25-21,25-22) | Box score |
| 10/22/21 | Ashland, Ore. | Southern Oregon 3, Bushnell 0 (25-23,25-23,25-12) | Box score |
| 10/16/21 | Kirkland, Wash. | Northwest (Wash.) 3, Southern Oregon 2 (28-26,23-25,20-25,25-18,16-14) | Box score |
| 10/15/21 | Olympia, Wash. | Evergreen 3, Southern Oregon 1 (13-25,25-17,25-18,25-17) | Box score |
| 10/09/21 | Ashland, Ore. | Southern Oregon 3, Lewis-Clark State 2 (24-26,22-25,25-15,25-12,15-12) | Box score |
| 10/08/21 | Ashland, Ore. | Southern Oregon 3, Walla Walla 0 (25-12,25-13,25-18) | Box score |
| 10/06/21 | Ashland, Ore. | Oregon Tech 3, Southern Oregon 2 (25-22,25-19,24-26,23-25,15-10) | Box score |
| 10/02/21 | Portland, Ore. | Southern Oregon 3, Multnomah 0 (25-20,25-17,25-15) | Box score |
| 10/01/21 | Portland, Ore. | Southern Oregon 3, Warner Pacific 1 (25-13,25-22,23-25,25-15) | Box score |
| 09/25/21 | Ashland, Ore. | Eastern Oregon 3, Southern Oregon 1 (25-19,19-25,25-21,25-13) | Box score |
| 09/24/21 | Ashland, Ore. | College of Idaho 3, Southern Oregon 2 (21-25,25-23,25-27,25-23,15-13) | Box score |
| 09/18/21 | Eugene, Ore. | Bushnell 3, Southern Oregon 0 (25-22,25-13,25-19) | Box score |
| 09/17/21 | Salem, Ore. | Corban 3, Southern Oregon 2 (24-26,25-17,25-17,16-25,15-10) | Box score |
| 09/14/21 | Klamath Falls, Ore. | Oregon Tech 3, Southern Oregon 0 (25-22,25-23,25-11) | Box score |
| 09/11/21 | Ashland, Ore. | Evergreen 3, Southern Oregon 0 (27-25,25-15,25-20) | Box score |
| 09/10/21 | Ashland, Ore. | Northwest (Wash.) 3, Southern Oregon 2 (15-25,25-19,15-25,25-18,16-14) | Box score |
| 09/04/21 | College Place, Wash. | Southern Oregon 3, Walla Walla 0 (25-10,25-6,25-16) | Box score |
| 09/03/21 | Lewiston, Idaho | Southern Oregon 3, Lewis-Clark State 0 (25-23,25-10,25-17) | Box score |
| 08/28/21 | Rocklin, Calif. | Southern Oregon 3, Simpson 0 (25-22,25-9,25-23) | Box score |
| 08/28/21 | Rocklin, Calif. | Southern Oregon 3, William Jessup 2 (20-25,25-22,20-25,25-17,15-6) | Box score |
| 08/27/21 | Rocklin, Calif. | Southern Oregon 3, UC Merced 0 (25-19,25-23,25-15) | Box score |
| 08/27/21 | Rocklin, Calif. | Southern Oregon 3, Menlo 0 (25-17,25-21,25-16) | Box score |
| 08/19/21 | Ashland, Ore. | Southern Oregon 3, Simpson 0 (25-17,25-10,25-16) | Box score |